<Emphasis Type="Italic">Pseudomonas aeruginosa</Emphasis> Cystic Fibrosis isolates of similar RAPD genotype exhibit diversity in biofilm forming ability <Emphasis Type="Italic">in vitro</Emphasis>期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Pseudomonas aeruginosa Cystic Fibrosis isolates of similar RAPD genotype exhibit diversity in biofilm forming ability in vitro

Authors:	Elena Deligianni Sally Pattison Daniel Berrar Nigel G Ternan Richard W Haylock John E Moore Stuart J Elborn James SG Dooley

Affiliation:	(1) Infection and Immunity Research Group, School of Biomedical Sciences, University of Ulster, BT52 1SA, Cromore Road, Coleraine, Northern Ireland, UK;(2) Dentistry and Biomedical Sciences, School of Medicine, Queen's University of Belfast, BT7 1NN, 73 University Road, Belfast, Northern Ireland, UK;(3) Systems Biology Research Group, School of Biomedical Sciences, University of Ulster, Road, Coleraine, BT52 1SA, Northern Ireland, UK;(4) Department of Bacteriology, Belfast City Hospital, Northern Ireland Public Health Laboratory Service, BT9 7AD Belfast, Northern Ireland, UK

Abstract:	Background Pseudomonas aeruginosa is considered to grow in a biofilm in cystic fibrosis (CF) chronic lung infections. Bacterial cell motility is one of the main factors that have been connected with P. aeruginosa adherence to both biotic and abiotic surfaces. In this investigation, we employed molecular and microscopic methods to determine the presence or absence of motility in P. aeruginosa CF isolates, and statistically correlated this with their biofilm forming ability in vitro.

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