Reactive oxygen species mediate lethality induced by far-UV in Escherichia coli cells |
| |
Authors: | Gomes A A Silva-Júnior A C T Oliveira E B Asad L M B O Reis N C S C Felzenszwalb I Kovary K Asad N R |
| |
Affiliation: | Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, 20551-030 Rio de Janeiro, RJ, Brazil. |
| |
Abstract: | The involvement of reactive oxygen species (ROS) in the induction of DNA damage to Escherichia coli cells caused by UVC (254 nm) irradiation was studied. We verified the expression of the soxS gene induced by UVC (254 nm) and its inhibition by sodium azide, a singlet oxygen (1O2) scavenger. Additional results showed that a water-soluble carotenoid (norbixin) protects against the lethal effects of UVC. These results suggest that UVC radiation can also cause ROS-mediated lethality. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|