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Identification of aminopiperidine benzamides as MCHr1 antagonists |
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| Authors: | Vasudevan Anil Verzal Mary K Wodka Derek Souers Andrew J Blackburn Christopher Che Jennifer Lee Lai Sujen Brodjian Sevan Falls Doug H Dayton Brian D Govek Elizabeth Daniels Tom Geddes Brad Marsh Kennan C Hernandez Lisa E Collins Christine A Kym Philip R |
| Institution: | Metabolic Diseases Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA. anil.vasudevan@abbott.com |
| Abstract: | The identification of a novel series of benzamide-containing MCHr1 antagonists is described. Compound 22 displayed moderate efficacy in a diet induced obesity mice model. |
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