Qualitative Complementation Test for Temperature-Sensitive Mutants of Herpes Simplex Virus |
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| Authors: | Chien-Ts Chu and Priscilla A. Schaffer |
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| Affiliation: | Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas 77025 |
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| Abstract: | A simple, rapid, qualitative method for classifying temperature-sensitive mutants of herpes simplex virus into functional complementation groups has been developed. The positive reaction observed in this test reflects the ability of mutant pairs to interact by both complementation and recombination. |
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