Aggregation of calcium ionophore (A23187) in phospholipid vesicles |
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| Authors: | S V Balasubramanian K R Easwaran |
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| Affiliation: | Molecular Biophysics Unit, Indian Institute of Science, Bangalore. |
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| Abstract: | The circular dichroism studies on calcium ionophore, A23187, incorporated in Dipalmitoyl phosphatidyl choline (DPPC) vesicle showed interesting time dependent changes in the CD spectra. Analysis of the data indicated the possible aggregation of the observed dimeric structure of this molecule in non-polar solvents into a stacked dimeric pore in the phospholipid vesicle. |
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