Regulation of cyclic AMP in heart and gill of Aplysia by the putative neurotransmitters dopamine and serotonin.期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Regulation of cyclic AMP in heart and gill of Aplysia by the putative neurotransmitters dopamine and serotonin.

Authors:	P R Kebabian J W Kebabian D O Carpenter

Institution:	1. Neurobiology Department Armed Forces Radiobiology Research Institute Bethesda, Maryland 20014, USA;2. National Institute of Neurological and Communicable Diseases and Stroke National Institutesof Health Bethesda, Maryland 20014, USA

Abstract:	Serotonin (5-HT) and dopamine (DA), but not several other putative neurotransmitters, stimulate cyclic adenosine-3',5'-monophosphate (cAMP) production in slices of $Aplysia$ gill. Furthermore, 5-HT but not DA increases cAMP in slices of the heart of $Aplysia$ . Several lines of evidence indicate that the receptors are distinct entities; however, no drugs were found to block one receptor without affecting the other.

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