Ultrastructure of isolated mouse ovarian follicles cultured in vitro |
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Authors: | Stefania A Nottola Sandra Cecconi Serena Bianchi Cecilia Motta Gianna Rossi Maria A Continenza Guido Macchiarelli |
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Affiliation: | (1) Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, “La Sapienza” University of Rome, Rome, Italy;(2) Department of Health Sciences, University of L’Aquila, L’Aquila, Italy;(3) Centre of Microscopy, University of L’Aquila, L’Aquila, Italy |
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Abstract: | Background In vitro maturation of ovarian follicles, in combination with cryopreservation, might be a valuable method for preserving and/or restoring fertility in mammals with impaired reproductive function. Several culture systems capable of sustaining mammalian follicle growth in vitro have been developed and many studies exist on factors influencing the development of in vitro grown oocytes. However, a very few reports concern the ultrastructural morphology of in vitro grown follicles. |
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