Novel urease inhibitors from Daphne oleoids |
| |
| Authors: | Ayaz Muhammad Lodhi Muhammad Arif Riaz Muhammad Ul-haq Azhar Malik Abdul Choudhary M Iqbal |
| |
| Institution: | HEJ Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi 75270, Pakistan. |
| |
| Abstract: | Phytochemical investigations on the chloroform and ethyl acetate soluble fractions of the roots of the Daphne oleoids led to the isolation of the coumarin glycosides 1-6. Compound 5 with IC50 values 22.05 and 26.30 microM repectively, was found to be the most active of these compounds when screened against Bacillus pasteurii and jack bean urease enzymes in a concentration-dependent fashion. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
