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Changes in levels of amino acid acceptors in tRNA from Escherichia coli grown under various conditions
Authors:R Chase  G M Tener  I C Gillam
Institution:1. Departments of Pharmacology and Medicine, Biochemistry, University of Washington School of Medicine Seattle, Washington 98195, USA;2. Sloan-Kettering Institute, New York, New York 10023 USA
Abstract:Active enzyme sedimentation of five asparaginase and glutaminase-asparaginase enzymes with antitumor activity was studied. The catalytically active species of each enzyme appeared to have a molecular weight greater than 100,000 g/mole. Gel filtration and disc gel electrophoresis confirmed the absence of catalytically active smaller species.
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