On the association between chromosomal rearrangements and genic evolution in humans and chimpanzees |
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Authors: | Tomàs Marques-Bonet,Jesús Sànchez-Ruiz,Lluís Armengol,Razi Khaja,Jaume Bertranpetit,Núria Lopez-Bigas,Mariano Rocchi,Elodie Gazave,Arcadi Navarro |
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Affiliation: | Tomàs Marques-Bonet, Jesús Sànchez-Ruiz, Lluís Armengol, Razi Khaja, Jaume Bertranpetit, Núria Lopez-Bigas, Mariano Rocchi, Elodie Gazave, and Arcadi Navarro |
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Abstract: | Background The role that chromosomal rearrangements might have played in the speciation processes that have separated the lineages of humans and chimpanzees has recently come into the spotlight. To date, however, results are contradictory. Here we revisit this issue by making use of the available human and chimpanzee genome sequence to study the relationship between chromosomal rearrangements and rates of DNA sequence evolution. |
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