Functional morphology of suprachiasmatic nuclei neurons of rat hypothalamus after the combined influence of x-irradiation and light exposure |
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Authors: | Gerasimov A V |
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Institution: | Siberian State Medical University, Tomsk, 634050 Russia. |
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Abstract: | For estimation of light radiomodification and cellular neuroadaptation of the circadian pacemarker, the morphological changes of suprachiasmatic nuclei (SCN) neurons of rat hypothalamus after 48-hours bright light exposure, the single 5 Gy whole-body X-irradiation and their combination were subjected to analysis. The dynamics of reactive and reparative changes has got a phasic character. Temporary desynchronous changes were developed in the course of the early period. Age morphological changes after X-ray and combined irradiation were discovered in the remote period. The plastic diapason of ventrolateral division (SCNv) is more considerable in comparison with dorsomedial division (SCNd). The synergism of X-irradiation and light exposure was discovered in SCNd. |
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