No effects of UMTS exposure on the function of rat outer hair cells |
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Authors: | Paolo Galloni Vanni Lopresto Marta Parazzini Rosanna Pinto Marta Piscitelli Paolo Ravazzani Carmela Marino |
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Institution: | 1. Toxicology and Biomedical Sciences Unit, Enea Casaccia Research Center, Rome, Italy;2. Institute of Biomedical Engineering ISIB, Italian National Research Council, Milan, Italy |
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Abstract: | UMTS communication devices are becoming common in everyday use. This could raise public concern about their possible detrimental effects on human health. The aim of this study, in the framework of the EMF nEAR Project, was to evaluate possible influence of UMTS electromagnetic fields (EMF) exposure on cochlear outer hair cells' (OHCs) functionality in laboratory animals. Forty‐eight male Sprague–Dawley rats were locally exposed (right ear) or sham‐exposed to a controlled UMTS EMF, frequency of 1946 MHz, at SAR level of 10 W/kg, 2 h a day, 5 days a week, for 4 weeks. A group of 12 rats treated with kanamycin (KM) was also included as positive control. Rats were tested by recording Distortion Product Otaoacoustic Emissions (DPOAEs), a non‐invasive test capable of assessing the status of the OHCs in the inner ear. DPOAEs were performed before, during (one or three times a week) and after (1‐week) exposure to the EMF. The analysis of the data shows that no statistically significant differences were found between the audiological signals recorded from the different experimental groups. The ototoxic effect of KM has been confirmed. Bioelectromagnetics 30:385–392, 2009. © 2009 Wiley‐Liss, Inc. |
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Keywords: | mobile phones radiofrequency cochlea otoacoustic emissions rodents |
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