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A novel high‐throughput cell‐based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery
Authors:David N Nguyen  Phillip Kim  Luis Martínez‐Sobrido  Brett Beitzel  Adolfo García‐Sastre  Robert Langer  Daniel G Anderson
Institution:1. Division of Health Sciences and Technology, MIT, Cambridge, Massachusetts;2. Department of Chemical Engineering, MIT, Cambridge, Massachusetts;3. Department of Microbiology, Mount Sinai School of Medicine, New York, New York;4. US Army Medical Research Institute of Infectious Disease, Ft. Detrick, Maryland;5. Department of Medicine, Division of Infectious Diseases, Mount Sinai School of Medicine, New York, New York;6. Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York, New York;7. David H. Koch Institute for Integrative Cancer Research, MIT, E25‐342, 45 Carleton St., Cambridge, Massachusetts 02139;8. telephone: 617‐258‐0397;9. fax: 617‐258‐8827
Abstract:
Keywords:RNA interference  siRNA  immunostimulatory RNA  drug delivery  high‐throughput screening  innate immunity
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