Antibacterial peptide nisin: A potential role in the inhibition of oral pathogenic bacteria |
| |
| Affiliation: | 1. Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China;2. Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China;3. Department of Conservative Dentistry & Endodontics, School of Stomatology, Fourth Military Medical University, Xi’an, Shaanxi, China;1. Guangdong Provincial Key Laboratory of Stomatology, Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China;2. Department of Endodontics, The Dental College of Georgia, Augusta University, GA, USA;3. State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Oral Diseases, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi’an, PR China;4. Department of Oral and Maxillofacial Surgery, The Dental College of Georgia, Augusta University, GA, USA;1. Hubei Collaboration Innovation Center of Non-power Nuclear Technology, Hubei University of Science and Technology, Xianning 437100, China;2. College of Chemical Engineering, Wuhan University of Technology, Wuhan 430070, China;3. School of Nuclear Technology & Chemistry and Biology, Hubei University of Science and Technology, Xianning 437100, China;1. Department of Cariology, Restorative Sciences, and Endodontics, School of Dentistry, University of Michigan, Ann Arbor, Michigan;2. Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan;3. Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan;4. Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan;5. Department of Surgical Sciences, Marquette University, School of Dentistry, Milwaukee, Wisconsin;6. Department of Orofacial Sciences, Division of Periodontology, University of California San Francisco, San Francisco, California |
| |
| Abstract: | Although the antimicrobial peptide nisin has been extensively studied in the food industry for decades, its application in the oral cavity remains to develop and evaluate its feasibility in treating oral common diseases. Nisin is an odorless, colorless, tasteless substance with low toxicity and with antibacterial activities against Gram-positive bacteria. These biologic properties may establish its use in promising products for oral diseases. This article summarizes the antibacterial efficiency of nisin against pathogenic bacteria related to dental caries and root canal infection and discusses the combination of nisin and common oral drugs. |
| |
| Keywords: | Nisin MTAD MTADN |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
