Known data on applied regenerative medicine in tendon healing |
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Authors: | Amit Lakhani Ena Sharma Amit Kapila Kavin Khatri |
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Institution: | 1.Dr Br Ambedkar State Institute of Medical Sciences, Mohali Punjab, India;2.Maharishi Markandeshwar College of Dental Sciences and Hospital Mullana, Ambala, Haryana, India;3.Consultant Fortis Hospital, Mohali, India;4.All India Institute of Medical Sciences, Bathinda, Punjab, India |
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Abstract: | Tendons and ligaments are important structures in the musculoskeletal system. Ligaments connect various bones and provide stability in complex movements of joints in the knee. Tendon is made of dense connective tissue and transmits the force of contraction from muscle to bone. They are injured due to direct trauma in sports or roadside accidents. Tendon healing after repair is often poor due to the formation of fibro vascular scar tissues with low mechanical property. Regenerative techniques such as PRP (platelet-rich plasma), stem cells, scaffolds, gene therapy, cell sheets, and scaffolds help augment repair and regenerate tissue in this context. Therefore, it is of interest to document known data (repair process, tissue regeneration, mechanical strength, and clinical outcome) on applied regenerative medicine in tendon healing. |
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Keywords: | Tendon ligament ACL PRP stem cells scaffolds gene therapy |
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