Variation of antimetabolite sensitivity with different carbon sources inBacillus subtilis |
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Authors: | A. Chaudhuri A. K. Mishra G. Nanda |
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Affiliation: | (1) Department of Microbiology, Bose Institute, 700 009 Calcutta, India |
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Abstract: | The susceptibility ofBacillus subtilis to amino acid analogues was found to be markedly influenced by the carbon source used in the test media. Thialysine inhibited the bacterium with a greater number of carbon sources than the other two analogues tested. 5-Hydroxylysine was inhibitory with glycerol, lactose,D-xylose,L-arabinose and soluble starch while ethionine showed toxicity with lactose,D-xylose andL-arabinose. None of these analogues were toxic at the levels tested whenD-galactose was used as carbon source. The bacterium was not susceptible to thialysine with glycerol, to 5-hydroxylysine withL-arabinose and to ethionine with lactose. |
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