Siderophore mediated iron(III) uptake in Gliocladium virens. 2. Role of ferric mono- and dihydroxamates as iron transport agents |
| |
| Authors: | M A Jalal S K Love D van der Helm |
| |
| Institution: | 1. Division of Biotechnology and Phycology, CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar 364002, Gujarat, India;2. Academy of Scientific & Innovative Research (AcSIR), CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar 364002, Gujarat, India;1. Laboratory of Histological Analysis and Preparation (LAPHis), Federal University of Piauí, Parnaíba, PI, Brazil;2. Laboratory of Experimental Physiopharmacology (LAFFEX), Federal University of Piauí, Parnaíba, PI, Brazil;3. Laboratory of Biochemistry and Biology of Microorganism and Plants (BIOMIC), Federal University of Piauí, Parnaíba, PI, Brazil;4. Laboratory of Molecular Biology and Biochemistry, Federal University of Ceará, Fortaleza, CE, Brazil |
| |
| Abstract: | The Fe(III) transport properties of the monohydroxamates, cis-fusarinine (cF) and trans-fusarinine (tF), and the dihydroxamate, dimerum acid (DA), the major siderophores of the fungus, Gliocladium virens ATCC 24290, have been investigated using labeled ferric siderophores. Fe(cF)3, Fe(tF)3 and Fe2(DA)3 (and also one of the minor trihydroxamates, ferricrocin) transport extracellular 55Fe(III) very efficiently into the fungus. Coprogen, another minor trihydroxamate, behaves as a weak Fe(III)-transporting agent. The respiratory poisons, KCN and NaN3, significantly inhibit uptake activity, indicating that the Fe(III) uptake mediated by Fe(cF)3, Fe(tF)3, and Fe2(DA)3 involves active transport systems in the membrane. A number of fungal species, both producers and nonproducers of cF, tF, and DA, show ability at varying degrees to transport 55Fe(III) bound to these siderophores. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
