Metabolic reconstruction of sulfur assimilation in the extremophile <Emphasis Type="Italic">Acidithiobacillus ferrooxidans</Emphasis> based on genome analysis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Metabolic reconstruction of sulfur assimilation in the extremophile Acidithiobacillus ferrooxidans based on genome analysis

Authors:	Jorge?Valdés,Felipe?Veloso,Eugenia?Jedlicki,David?Holmes author-information" > author-information__contact u-icon-before" > mailto:dsholmes@yahoo.com" title=" dsholmes@yahoo.com" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author

Affiliation:	(1) Laboratory of Bioinformatics and Genome Biology, University of Santiago (USACH), Santiago, Chile;(2) Program of Cellular and Molecular Biology, I.C.B.M., Faculty of Medicine, University of Chile, Santiago, Chile;(3) Millennium Institute of Fundamental and Applied Biology, Santiago, Chile

Abstract:	Background Acidithiobacillus ferrooxidansis a gamma-proteobacterium that lives at pH2 and obtains energy by the oxidation of sulfur and iron. It is used in the biomining industry for the recovery of metals and is one of the causative agents of acid mine drainage. Effective tools for the study of its genetics and physiology are not in widespread use and, despite considerable effort, an understanding of its unusual physiology remains at a rudimentary level. Nearly complete genome sequences ofA. ferrooxidansare available from two public sources and we have exploited this information to reconstruct aspects of its sulfur metabolism.

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