| 家蚕血液对BmE-SWU1细胞凋亡的抑制作用 |
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| 引用本文： | 潘敏慧,邓为科,陈默,张金叶,杜娟,鲁成.家蚕血液对BmE-SWU1细胞凋亡的抑制作用[J].动物学报,2008,54(5). |
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| 作者姓名： | 潘敏慧 邓为科 陈默 张金叶 杜娟 鲁成 |
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| 作者单位： | 西南大学,蚕学与系统生物学研究所,重庆,400716 |
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| 基金项目： | 国家自然科学基金，重庆市自然科学基金 |
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| 摘 要： | 以家蚕胚胎细胞系BmE-SWU1细胞为体外模型,用不同浓度的放线菌素D处理家蚕BmE-SWU1细胞进行家蚕细胞凋亡研究.结果表明:放线菌素D诱导家蚕细胞凋亡的作用呈时间、剂量依赖性.分别用浓度为0、50、100和200 ng/ml的放线菌素D处理BmE-SWU1细胞12 h后,凋亡峰所占比例分别为1.82%、1.26%、8.21%和12.31%.当放线菌素D的浓度为100 ng/ml时,诱导家蚕BmE-SWU1细胞凋亡的效果显著;家蚕血液对放线菌素D诱导的家蚕BmE-SWU1细胞凋亡具有明显的抑制作用.
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| 关 键 词： | 家蚕 家蚕血液 BmE-SWU1细胞系 细胞凋亡 凋亡抑制 |
Inhibition of BmE-SWU1 cell apoptosis by silkworm hemolymph |
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| PAN Min-Hui,DENG Wei-Ke,CHEN Mo,ZHANG Jin-Ye,DU Juan,LU Cheng.Inhibition of BmE-SWU1 cell apoptosis by silkworm hemolymph[J].Acta Zoologica Sinica,2008,54(5). |
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| Authors: | PAN Min-Hui DENG Wei-Ke CHEN Mo ZHANG Jin-Ye DU Juan LU Cheng |
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| Institution: | PAN Min-Hui,DENG Wei-Ke,CHEN Mo,ZHANG Jin-Ye,DU Juan,LU ChengInstitute of Sericulture , Systems Biology,Southwest University,Chongqing 400716,China |
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| Abstract: | It is important to reveal the mechanisms of developmental biology and genic control for absolutely metamorphic insects,as well as to research sericulture science,that apoptosis of Bombyx mori was researched with BmE-SWU1 cells treated with various concentration of Actinomycin D.After BmE-SWU1 cells were treated with various concentration of Actinomycin D,the effects of apoptosis depend on time and dose in BmE-SWU1 cells and the apoptosis is very significant when cells were treated with Actinomycin D 12 h at... |
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| Keywords: | Bombyx mori Silkworm hemolymph BmE-SWU1 cell line Apoptosis Inhibition of apoptosis |
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