On the possibility of pleiotropic monogenic control of hereditary polyposis and primary cancer of the colon. |
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| Authors: | E K Ginsburg T I Axenovich B A Altshouler and M D Bazhenova |
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| Institution: | Institute of Cytology and Genetics, Academy of Sciences of the USSR, Siberian Division, Novosibirsk. |
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| Abstract: | The results of the segregation analysis of hereditary adenomatous polyposis and primary cancer of the colon are given, taking into account the age-dependent manifestation of genotypes and the specificity of pedigree sampling. The results are used for testing the hypothesis of pleiotropic monogenic control of these two colon pathologies. |
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