The RAD52 gene is not required for the function of the DEL1 mutator gene in Saccharomyces cerevisiae |
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Authors: | Susan W. Liebman and Karen M. Downs |
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Affiliation: | (1) Department of Biological Sciences, University of Illinois at Chicago Circle, Box 4348, 60680 Chicago, Illinois, USA |
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Abstract: | Summary The DEL1 mutator in Saccharomyces cerevisiae leads to the formation of deletions adjacent to itself (Liebman et al. 1979). Here we show that the frequency of these DEL1-promoted deletions is not altered by the presence of the recombination-deficient mutation, rad52-1. This indicates that generalized recombination is not required for the formation of deletions in DEL1 yeast strains. |
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