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Facile synthesis of 2-aryl 5-hydroxy benzo[d]oxazoles and their in vitro anti-proliferative effects on various cancer cell lines |
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| Authors: | Neelima D. Tangellamudi Suchita B. Shinde Venkatesh Pooladanda Chandraiah Godugu Sridhar Balasubramanian | |
| Affiliation: | 1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Hyderabad 500037, India;2. Department of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research, Hyderabad 500037, India;3. Indian Institute of Chemical Technology, Hyderabad 500607, India | |
| Abstract: | 2-Aryl 5-hydroxy benzo[d]oxazoles were designed as potential anticancer agents. A one-pot synthesis of these compounds dispenses the need for ortho-disubstituted precursor, aminophenol and proceeds via C | |
| Keywords: | Aza-Michael attack Quinol Cytotoxicity | |
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