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Occurrence of meso-alpha, epsilon-diaminopimelate dehydrogenase in Bacillus sphaericus.
Authors:H Misono  H Togawa  T Yamamoto  K Soda
Institution:Laboratory of Microbial Biochemistry, Institute for Chemical Research, Kyoto University, Uji, Kyoto-Fu 611, Japan
Abstract:A new amino acid dehydrogenase catalyzing the oxidative deamination of meso-α,?-diaminopimelate was found in the crude extract of Bacillus sphaericus IFO 3525. This dehydrogenase requiring NADP was specific for meso-diaminopimelate and the other isomers were not substrates. The enzyme was optimally active at about pH 10.5. NAD could not replace NADP.
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