|
|||||
|
|
In vivo localization of insulin binding to cells of the rat pancreas |
|
| Authors: | C Sakamoto J A Williams E Roach I D Goldfine |
| Abstract: | The uptake of 125I-insulin by rat pancreas was studied in vivo. Following fixation and light microscope autoradiography, saturable uptake of 125I-insulin was quantitatively demonstrated on acinar and duct cells but not on blood vessels and islets of Langerhans. Electron microscopy revealed the localization of 125I-insulin to the basolateral cell membranes of acinar and duct cells. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |