gemini: software for testing the effects of genotyping errors and multitubes approach for individual identification |
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Authors: | Nathaniel Vali re,Pierre Berthier,Dominique Mouchiroud,Dominique Pontier |
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Affiliation: | Nathaniel Valière,Pierre Berthier,Dominique Mouchiroud,Dominique Pontier |
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Abstract: | Improvements in the determination of individual genotypes from samples with low DNA quantity and quality are of prime importance in molecular ecology and conservation for reliable genetic individual identification (molecular tagging using microsatllites loci). Thus, errors (e.g. allelic dropout and false allele) appearing during samples genotyping must be monitored and eliminated as far as possible. The multitubes approach is a very effective but a costly and time‐consuming solution. In this paper, we present a simulation software that allows evaluation of the effect of genotyping errors on genetic identification of individuals and the effectiveness of a multitubes approach to correct these errors. |
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Keywords: | allelic dropout false allele genotyping errors individual identification multitubes approach software |
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