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Surface marker characterization of EBV target cells in normal blood and tonsil B lymphocyte populations
Authors:P Aman  J Gordon  N Lewin  M Nordstr?m  B Ehlin-Henriksson  G Klein  A Carstensson
Abstract:Human FACS-sorted B lymphocyte subpopulations were investigated for their susceptibility to immortalization by Epstein Barr virus (EBV). Only B cells reacting with the monoclonal antibody B2 were immortalized, whereas cells reacting with anti-human IgG or the monoclonal antibody BB2 were not responding. Cells positive or negative for IgM, IgD, Burkitt's lymphoma antigen (BLA), BB1, and HB2 were all transformed by EBV.
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