Construction of low-resolution x-ray crystallographic electron density maps of the ribosome |
| |
| Authors: | Cate J H |
| |
| Affiliation: | Departments of Chemistry and Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA. jcate@lbl.gov |
| |
| Abstract: | Advances in X-ray crystallography now allow biological macromolecules of almost any size to be imaged at atomic resolution. Here, I outline the strategy that allowed for the solution of the 70S ribosome structure to 7.8-A resolution. The most important factors involve the effective use of synchrotron radiation and the application of existing crystallographic software to very large structures. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
