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Peptidergic innervation of the rat Harderian gland
Authors:S Tsukahara  D M Jacobowitz
Institution:(1) Department of Ophthalmology, Yamanashi Medical College, 409-38 Tamaho, Yamanashi, Japan;(2) Laboratory of Clinical Science, National Institute of Mental Health, Building 10, Room 3D-48, 20892 Bethesda, Maryland, USA
Abstract:Summary The immunohistochemical localization of vasoactive intestinal polypeptide (VIP), Neurotensin (NT), cholestokinin (CCK), Neuropeptide Y (NPY), and calcitonin-gene-related peptide (CGRP) in rat Harderian glands was examined. Numerous VIP- and CCK-like immunoreactive nerves were found in close apposition to the acini. Sparse numbers of NT-, NPY-, and CGRP-like immunoreactive nerves were observed in close proximity to the acini and blood vessels. Some VIP-like immunoreactive nerves were shown to be co-localized with acetylcholinesterasepositive cholinergic nerves.
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