| DA大鼠的繁殖性能及部分生物学特性参数的测定 |
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| 引用本文： | 王海霞,;李永明,;郭守利.DA大鼠的繁殖性能及部分生物学特性参数的测定[J].中国实验动物学杂志,2007(12):710-713. |
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| 作者姓名： | 王海霞 ;李永明 ;郭守利 |
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| 作者单位： | [1]哈医大二院动物实验中心,哈尔滨150086; [2]哈药集团制药总厂实验动物中心,哈尔滨150086 |
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| 基金项目： | 黑龙江省攻关课题（编号：SY02-07）. |
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| 摘 要： | 目的建立我国新的近交系品系DA种群，观察其生长繁殖性能及部分生物学特性。方法从丹麦M＆B公司引进近交系大鼠DA，建立种群，从其扩大群中随机抽取15对鼠，统计其繁殖率；抽取50只DA鼠（雌雄各半）测其部分血液生化。结果近交系种群扩大成功，DA大鼠平均产仔数为5．5，成活率为90.8％，所测生理生化值接近Wistar大鼠。结论DA大鼠已适应我国环境，种群引进成功；性别对脏器重量、系数和血生化影响显著。
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| 关 键 词： | 大鼠 DA 繁殖性能 脏器系数 心率 血压 |
Determination of Reproduction Ability and Biological Parameters in DA Rats |
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| Institution: | WANG Hai-xia, LI Yong-ming ,GUO Shou-li (1. Laboratory Animal Center,The Second Hospital of Harbin University,Harbin 150086,China; 2. Laboratory Animal Center of General Pharmaceutical Factory, Harbin Pharmaceutical Group Co. Ltd. Harbin 150086) |
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| Abstract: | Objective To establish a new inbred strain and observe the growth, fecundity and some biological characteristics of DA rats under a stable raising condition. Methods 15 pairs of DA rats were raised to observe their fecundity and 25 pairs of DA rats were raised to examine their blood Indices. The rats were imported from production stock in Danmark. Results The inbred strain of DA rats was successfully established. DA rats provided a litter size of 5.5 rats in average, survival rate of 90.8 %, and the blood indices were close to those of Wistar rats. Conclutsion DA rats have been adapted to the conditions of our animal center and the introduced strain is successful. However,attention should be paid to that some biochemical indices and organ weight and organ cofficents are affected by sex. |
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| Keywords: | Rat DA Reproduction ability Viscera coefficient Heart rate Blood pressure |
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