Metabolites ofStreptomyces noursei |
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| Authors: | K Mikulík M Půža |
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| Institution: | 1. Department of Biogenesis of Natural Substances, Institute of Microbiology, Czechoslovak Academy of Sciences, Prague 4
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| Abstract: | Branched chain amino acids are degraded byStreptomyces noursei to the corresponding amides: valine being the precursor of isobutyramide, leucine of isovaleramide and isoleucine of anteisovaleramide. The formation of amides is pyridoxalphosphate dependent and is catalyzed by peroxidase. Furthermore it was found that branched chain amino acids were also degraded via the corresponding 2-oxoacids into acylCoA which can be dehydrogenated to unsaturated acylCoA or hydrolyzed to acids and CoASH. |
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