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Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation
Affiliation:1. Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794, USA;2. Departments of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX 77030, USA;3. Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, TX 77030, USA;4. Advanced Technology Cores, Baylor College of Medicine, Houston, TX 77030, USA;5. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA;6. Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA;7. Center for Drug Discovery and Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA
Abstract:
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