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Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays
Affiliation:1. Center for Life Nano- & Neuro-Science, Istituto Italiano di Tecnologia, 00161 Rome, Italy;2. Department of Physiology and Pharmacology, Sapienza University, 00185 Rome, Italy;3. Soft and Living Matter Laboratory, Institute of Nanotechnology, Consiglio Nazionale delle Ricerche, 00185 Rome, Italy;4. CrestOptics S.p.A, 00165 Rome, Italy;5. Electron Microscopy Facility, Istituto Italiano di Tecnologia, 16163 Genova, Italy;6. Telethon Institute of Genetics and Medicine, 80078 Pozzuoli, Italy;7. Institute for Genetic and Biomedical Research, National Research Council, 20090 Milan, Italy;8. Institute of Biochemistry and Cellular Biology, National Research Council, 00015 Rome, Italy;9. Department of Biology and Biotechnologies “Charles Darwin”, Sapienza University, 00185 Rome, Italy;10. Santa Lucia Foundation (IRCCS Fondazione Santa Lucia), 00179 Rome, Italy;11. Department of Physics, Sapienza University, 00185 Rome, Italy;12. D-Tails s.r.l, 00165 Rome, Italy;13. Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA
Abstract:
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  • Keywords:activated microglia  alternatively activated microglia  microtubule  centrosome  γ-tubulin  MTOC  Golgi outposts  retina  inflammation  reactive microglia  CP: Neuroscience  CP: Molecular biology
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