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Two distinct gut microbial pathways contribute to meta-organismal production of phenylacetylglutamine with links to cardiovascular disease
Affiliation:1. Department of Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA;2. Center for Microbiome and Human Health, Cleveland Clinic, Cleveland, OH, USA;3. Department of Bioengineering and ChEM-H, Stanford University, Stanford, CA, USA;4. Case Western Reserve University, College of Arts and Sciences, Cleveland, OH, USA;5. Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA;6. Department of Chemistry, Cleveland State University, Cleveland, OH, USA
Abstract:
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  • Keywords:Atherosclerotic cardiovascular disease  gut microbes  phenylacetic acid  phenylalanine  phenylacetylglycine  phenylacetylglutamine  phenylpyruvate:ferredoxin oxidoreductase  phenylpyruvate decarboxylase
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