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Structural and functional analysis of a potent human neutralizing antibody against enterovirus A71 |
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| Authors: | Chen Zhe Bao Linlin Zhu Bin Fu Hua Zhu Shuangli Ji Tianjiao Xue Ying Liu Chuan Wang Xurong Li Fengdi Lv Qi Qi Feifei Yu Pin Deng Wei Xu Wenbo Qin Chuan Liu Hongrong Jin Qi |
| Institution: | 1.MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China ;2.Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, NHC Key Laboratory of Human Disease Comparative Medicine, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, 100021, China ;3.School of Computer Science and Engineering, Hunan University of Science and Technology, Xiangtan, 411201, China ;4.National Institute for Viral Disease Control and Prevention, China CDC, Beijing, 102206, China ;5.Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing, 100084, China ;6.Key Laboratory for Matter Microstructure and Function of Hunan Province, Key Laboratory of Low-dimensional Quantum Structures and Quantum Control, School of Physics and Electronics, Hunan Normal University, Changsha, 410081, China ;7.Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, 310058, China ; |
| Abstract: | Science China Life Sciences - Enterovirus A71 (EV-A71) causes major outbreaks of hand, foot, and mouth disease (HFMD) in many countries, most frequently affecting children, and a small proportion... |
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