Comparative computational analysis of ADP Glucose Pyrophosphorylase in plants

ADP-glucose pyrophosphorylase (AGPase), a key enzyme involved in higher plant starch biosynthesis, is composed of pairs oflarge (LS) and small subunits (SS). Ample evidence has shown that the AGPase catalyzes the rate limiting step in starchbiosynthesis in higher plants. In this study, we compiled detailed comparative information about ADP glucose pyrophosphorylasein selected plants by analyzing their structural features e.g. amino acid content, physico-chemical properties, secondary structuralfeatures and phylogenetic classification. Functional analysis of these proteins includes identification of important 10 to 20 aminoacids long motifs arise because specific residues and regions proved to be important for the biological function of a group ofproteins, which are conserved in both structure and sequence during evolution. Phylogenetic analysis depicts two main clusters.Cluster I encompasses large subunits (LS) while cluster II contains small subunits (SS).