Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices |
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Authors: | Betancourt Tania Brannon-Peppas Lisa |
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Institution: | Department of Biomedical, Engineering, The University of Texas at Austin, TX, USA. |
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Abstract: | Micro- and nanofabrication techniques have revolutionized the pharmaceutical and medical fields as they offer the possibility for highly reproducible mass-fabrication of systems with complex geometries and functionalities, including novel drug delivery systems and bionsensors. The principal micro- and nanofabrication techniques are described, including photolithography, soft lithography, film deposition, etching, bonding, molecular self assembly, electrically induced nanopatterning, rapid prototyping, and electron, X-ray, colloidal monolayer, and focused ion beam lithography. Application of these techniques for the fabrication of drug delivery and biosensing systems including injectable, implantable, transdermal, and mucoadhesive devices is described. |
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Keywords: | microfabrication nanofabrication medical devices drug delivery biosensors |
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