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Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases |
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| Authors: | Gallant Michel Beaulieu Christian Berthelette Carl Colucci John Crackower Michael A Dalton Chad Denis Danielle Ducharme Yves Friesen Richard W Guay Daniel Gervais François G Hamel Martine Houle Robert Krawczyk Connie M Kosjek Birgit Lau Stephen Leblanc Yves Lee Ernest E Levesque Jean-François Mellon Christophe Molinaro Carmela Mullet Wayne O'Neill Gary P O'Shea Paul Sawyer Nicole Sillaots Susan Simard Daniel Slipetz Deborah Stocco Rino Sørensen Dan Truong Vouy Linh Wong Elizabeth Wu Jin Zaghdane Helmi Wang Zhaoyin |
| Institution: | a Medicinal Chemistry, Merck Frosst Centre for Therapeutic Research, Kirkland, Québec, Canada b Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Québec, Canada c Basic Pharmaceutical Science, Merck Frosst Centre for Therapeutic Research, Québec, Canada d DMPK, Merck Frosst Centre for Therapeutic Research, Québec, Canada e Basic Pharmaceutical Science, Merck Research Laboratories, Rahway, NJ, USA |
| Abstract: | |
| Keywords: | MK-7246" target="_blank">MK-7246 CRTH2 antagonist DP2 antagonist Asthma Respiratory diseases |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |