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Computer analysis of two-dimensional gels
Authors:Kiem-Phong Vo  Mark J Miller  EPeter Geiduschek  Chris Nielsen  Arthur Olson
Institution:1. Department of Biology, University of California at San Diego, La Jolla, California 92093 USA;2. Department of Chemistry, University of California at San Diego, La Jolla, California 92093 USA;3. Department of Physics, University of California at San Diego, La Jolla, California 92093 USA
Abstract:New methods and computer programs are described which enable one to analyze autoradiograms produced by two-dimensional gel electrophoresis. These programs are completely automatic with respect to finding spots resolved by such gels and quantitating the radioactivity in them. Semiautomatic programs have also been developed to match the spot patterns of different autoradiograms, and to follow the synthesis of any individual polypeptide through a series of gels.
Keywords:Author to whom correspondence should be addressed  
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