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Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuni |
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| Authors: | Barbro Lindmark Pramod Kumar Rompikuntal Karolis Vaitkevicius Tianyan Song Yoshimitsu Mizunoe Bernt Eric Uhlin Patricia Guerry and Sun Nyunt Wai |
| Institution: | (1) Department of Molecular Biology, Ume? University, S-90187 Ume?, Sweden;(2) Department of Bacteriology, the Jikei University School of Medicine, 105-8461 Tokyo, Japan;(3) Laboratory for Molecular Infection Medicine Sweden (MIMS), Ume? University, S-90187 Ume?, Sweden;(4) Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Ave, Silver Spring, MD, USA |
| Abstract: | BackgroundBackground: Cytolethal distending toxin (CDT) is one of the well-characterized virulence factors of Campylobacter jejuni, but it is unknown how CDT becomes surface-exposed or is released from the bacterium to the surrounding environment. |
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