Plasma catecholamine and nephrine responses to brief intermittent maximal intensity exercise |
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Authors: | Richard M. Bracken Denise M. Linnane Stephen Brooks |
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Affiliation: | (1) Research Centre for Sport and Exercise Science, School of Human Sciences, Swansea University, Singleton Park, Swansea, SA2 8PP, UK;(2) Centre for Human Sciences, QinetiQ, Building A50, Cody Technology Park, Ively Road, Farnborough, Hampshire, GU14 0LX, UK;(3) Department of Physiology and Sport Sciences, Faculty of Health and Human Sciences, Coventry University, Priory St., Coventry, CV1 5FB, UK |
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Abstract: | Catecholamines (noradrenaline, NA; adrenaline, AD; dopamine, DA) influence the metabolic and cardiovascular responses to exercise. However, changes in catecholamine metabolism during exercise are unclear. Plasma normetanephrine (NMET), metanephrine (MET) and catecholamine responses to a laboratory-based model of games-type exercise were examined. Twelve healthy men completed a resting control trial and a trial consisting of ten 6 s cycle ergometer sprints interspersed with 30 s recovery, in randomised order. Resting and post-sprint venous blood samples were taken. Plasma NA and AD increased after each sprint but DA was unaltered. Plasma nephrines increased significantly from sprint 4 onwards with peak NMET increasing 60% to 0.76 ± 0.19 nmol l−1 and MET 230% to 0.37 ± 0.16 nmol l−1 from resting values (P < 0.05). The results demonstrate increased catecholamine metabolism via elevated catechol-O-methyl transferase activity during intermittent sprinting. The results may aid regulation of the metabolic and cardiovascular responses to exercise by maintaining tissue adrenoceptor sensitivity to circulating catecholamines. |
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