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Bactericidal activity of granules isolated from amoebocytes of the horseshoe crab, Limulus polyphemus
Authors:R H Smith  T G Pistole
Affiliation:Department of Microbiology, University of New Hampshire, Durham, New Hampshire 03824 USA
Abstract:Granules were isolated from amoebocytes of Limulus polyphemus and used in bactericidal studies. Whole granules, but not granular lysates, exhibited marked killing activity against Escherichia coli and Staphylococcus aureus. These findings support the idea that amoebocytes are an important component in the defense system of this animal.
Keywords:amoebocyte granules  bactericidal activity  Limulus polyphemus  Staphylococcus aureus
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