Effect of neocuproine and cuprizone on the development of amine oxidase and growth in pea seedlings

Effects of neocuproine (2,9-dimethyl-l,10-phenanthroline) andcuprizone (biscyclohexanone oxalyldihydrazone), as copper-chelatingagents on the development of amine oxidase and the growth ofpea plants were studied. Amine oxidase development in the apicalpart was inhibited by administration of neocuproine, and thiseffect was markedly reversed by the addition of copper disodiumethylenediaminetetraacetate(EDTA-Na₂-Cu). In this case, theamine oxidase activity was stimulated. Pea plant growth wasinhibited by this chelator but not in the presence of EDTA-Na₂-Cu.On the other hand, the development of enzyme activity and growthwere much less sensitive to cuprizone. (Received August 8, 1976; )