Measure of synonymous codon usage diversity among genes in bacteria |
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| Authors: | Haruo Suzuki Rintaro Saito Masaru Tomita |
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| Affiliation: | (1) Institute for Advanced Biosciences, Keio University, Tsuruoka Yamagata, 997-0017, Japan;(2) Systems Biology Program, Graduate School of Media and Governance, Keio University, Fujisawa Kanagawa, 252-8520, Japan |
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| Abstract: | Background In many bacteria, intragenomic diversity in synonymous codon usage among genes has been reported. However, no quantitative attempt has been made to compare the diversity levels among different genomes. Here, we introduce a mean dissimilarity-based index (Dmean) for quantifying the level of diversity in synonymous codon usage among all genes within a genome. |
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