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Adaptive evolution in a spatially structured asexual population
Authors:Isabel Gordo  Paulo R A Campos
Institution:Instituto Gulbenkian de Ciências, P-2781-901, Oeiras, Portugal.
Abstract:We study the process of adaptation in a spatially structured asexual haploid population. The model assumes a local competition for replication, where each organism interacts only with its nearest neighbors. We observe that the substitution rate of beneficial mutations is smaller for a spatially structured population than that seen for populations without structure. The difference between structured and unstructured populations increases as the adaptive mutation rate increases. Furthermore, the substitution rate decreases as the number of neighbors for local competition is reduced. We have also studied the impact of structure on the distribution of adaptive mutations that fix during adaptation.
Keywords:fixation  clonal interference  adaptation  spatial structure  local competition
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