Adaptive evolution in a spatially structured asexual population |
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Authors: | Isabel Gordo Paulo R A Campos |
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Institution: | Instituto Gulbenkian de Ciências, P-2781-901, Oeiras, Portugal. |
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Abstract: | We study the process of adaptation in a spatially structured asexual haploid population. The model assumes a local competition
for replication, where each organism interacts only with its nearest neighbors. We observe that the substitution rate of beneficial
mutations is smaller for a spatially structured population than that seen for populations without structure. The difference
between structured and unstructured populations increases as the adaptive mutation rate increases. Furthermore, the substitution
rate decreases as the number of neighbors for local competition is reduced. We have also studied the impact of structure on
the distribution of adaptive mutations that fix during adaptation. |
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Keywords: | fixation clonal interference adaptation spatial structure local competition |
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