The possible involvement of protein synthesis in the injection of PL-1 phage genome into its host, Lactobacillus casei. |
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Authors: | K Watanabe M Shirabe Y Nakashima Y Kakita |
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Affiliation: | Microbiology Laboratory, Faculty of Pharmaceutical Sciences, Fukuoka University, Japan. |
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Abstract: | The process of genome DNA injection, after adsorption, by phage PL-1 into host cells of Lactobacillus casei was monitored by using the electron microscope. Injection of DNA was inhibited by the protein-synthesis inhibitors chloramphenicol and erythromycin at concentrations where the colony-forming ability of cells not infected by phage was unaffected. The results suggest that protein synthesis may be involved in some way in the process of genome injection. |
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