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Fluorinated dihydroquinolines as potent n-NOS inhibitors |
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| Authors: | Jaroch Stefan Rehwinkel Hartmut Hölscher Peter Sülzle Detlev Burton Gerardine Hillmann Margrit McDonald Fiona M Miklautz Heribert |
| Affiliation: | Medicinal Chemistry, Corporate Research, Research Center Europe, Schering AG, D-13342-Berlin, Germany. stefan.jaroch@schering.de |
| Abstract: | Fluorinated dihydroquinolines showed reduced basicity of the amidine function. Their syntheses and potencies as neuronal nitric oxide synthase (n-NOS) inhibitors are reported. |
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