The binding of barium and calcium ions by the antibiotic beauvericin |
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Authors: | R W Roeske S Isaac T E King L K Steinrauf |
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Affiliation: | Department of Biochemistry and Biophysics Indiana University School of Medicine Indianapolis, Indiana 46202 USA |
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Abstract: | The ion-transporting antibiotic beauvericin has been shown to have a high affinity for calcium and barium ions in addition to the more usual affinity for monovalent cations. As judged by crystallization, extraction into organic solvent, and U-tube transport the cation selectivity is Rb>Ba>K>Na?Ca?Li. For these studies an improved method for the synthesis of beauvericin has been developed. |
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