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Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain‐antibody complex: Crystallographic,thermodynamic, and molecular dynamic analyses
Authors:Takefumi Yamashita  Satoru Nagatoishi  Makoto Nakakido  Hiroko Iwanari  Yasuhiro Mochizuki  Yuji Kado  Yuki Yokota  Reiko Satoh  Kouhei Tsumoto  Hideaki Fujitani  Tatsuhiko Kodama  Takao Hamakubo  Tsuyoshi Inoue
Affiliation:1. Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan;2. Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan;3. Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan;4. Structural Physical Chemistry, Division of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka, Japan
Abstract:
Keywords:antigen–  antibody interaction  antibody engineering  crystallography  molecular dynamics  thermodynamics
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