Insect antifeedant activity of clerodane diterpenes and related model compounds |
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Authors: | Klein Gebbinck Edwin A Jansen Ben J M de Groot Aede |
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Affiliation: | SelAct B.V., Nijenborgh 4, 9747 AG, Groningen, The Netherlands. |
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Abstract: | A comprehensive compilation of all test results on the insect antifeedant activity of clerodane diterpenes and related model compounds is reported. To increase the compatibility of data from different sources, some of the results reported in the literature have been converted into a standardized form. The compounds were sorted into groups according to the different types of sidechain attached to C-9. Despite the wealth of information, collected in 15 tables, it remains difficult to assign importance to separate structural elements in relation to the observed antifeedant activity. A detailed analysis of the structure-activity relationships could not be presented, but some interesting trends can be distinguished based on the structures of the strongest antifeedants. The compilation covers the literature up to December 2001. |
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Keywords: | Neo-clerodane diterpenes Bioactive metabolites Insect antifeedants Crop protection |
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