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Organelle size control systems: From cell geometry to organelle-directed medicine
Authors:Marshall Wallace F
Affiliation:Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA. wallace.marshall@ucsf.edu.
Abstract:Organelles are reaction vessels containing metabolic pathways. As in a chemical factory, the size of the reaction vessels limits the rate of product formation. Organelle size is tuned to metabolic needs, hence reprogramming organelle size could be a novel therapeutic strategy as well as a new tool for metabolic engineering.
Keywords:cytopathology  metabolic engineering  organelle size  scaling
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